Both World precipitation and temperature were extremely high this year.
The Peloponnesian war continued.
Plague kills over one-third of the population of Athens. Morale in the city, where people are engaging in, among other things, excessive drinking and lewd behavior, is low.
Hippocrates, the famous Greek physician, pioneers the field of modern medicine circa 429 B.C. by studying anatomy and physiology and by expanding medical vocabulary to include words such as chronic, crisis, convalescence, relapse,and exacerbate.
Darius, the king of Persia, lost 300 ships under general Mardonius (Herodotus "Histories" book VI (Erato), Aeschylus "The Persians") in the waters around Mount Athos.